Begin the lesson by introducing the concept of Biosphere 2 as a closed ecological system. Discuss its purpose and significance in studying human sustainability in closed environments.

Engage students with a brief discussion on Earth's unique biosphere and the idea of creating a second biosphere.

Explain the different biomes present in Biosphere 2, such as the rainforest, ocean, and desert, and their roles in the closed system.

Use the video 'The Earth's Biosphere' to illustrate the interconnectedness of Earth's spheres and how they sustain life.

Facilitate a discussion on the challenges and learnings from Biosphere 2 missions, focusing on the complexity and fragility of Earth's ecological systems.

Watch the video 'Earth's Four Spheres – Geosphere, Hydrosphere, Atmosphere and Biosphere' to understand how these spheres interact in sustaining life.

Conduct a hands-on activity where students create a mini ecosystem to observe processes such as evaporation and condensation, similar to those in Biosphere 2.

Assign students to research and describe one of the biomes in Biosphere 2, focusing on its climate, vegetation, and organisms.

Use the assessment 'Earth’s Spheres' to evaluate students' understanding of the interconnectedness of Earth's systems.

Encourage students to reflect on the significance of Biosphere 2's missions and how they relate to the sustainability of Earth's systems.

Conclude the lesson with a quiz to test comprehension of the topic.

For further exploration, students can engage in the 'Biome Research Project' to deepen their understanding of different ecological regions.